research project
Project Title: Synthesis and preliminary evaluation of novel gene delivery systems for tumour targeting
Project Description
Genetic therapies based on the understanding of the molecular biology of cancer hold the promise of safer and more efficacious anti-cancer medicines. In order to be able to exploit the full potential of such therapies, it is critical to be able to administer such therapies systemically, in a specific way, so that inaccessible tumours (i.e. metastases, inoperable brain tumours) can be treated. However, the lack of safe, efficacious and target-specific vectors is a major bottleneck for gene therapy to date.
The aims of this research project will be to synthesise and briefly evaluate targeted non-viral gene delivery systems. This project will involve “basic” chemistry, and an initiation to tissue culture and in vitro analysis.
Each student in the team will be allocated a different vector or targeting strategy, thus the group as a whole will be able to compare the preliminary data obtained.
posted by Cherie @ 10:58 pm
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